Depression is a common illness that can affect anyone, especially during this time of year. About one in twenty Americans (more than 11 million people) suffers from depression every year, and it occurs twice as often in women as in men. Depression is a medical disorder that can be treated.

Depression is a medical disorder, like heart disease and thyroid disease. It is more than feeling sad for a short time or feeling grief after a loss. These feelings are difficult to cope with, but they usually get better with time. Depression disrupts your daily life, and affects your thoughts, feelings, behavior and physical health. It is not a weakness, or a fault and it is not something you can ‘just get over’. Depression has been associated with many causes:

• Chemical imbalances in the brain
• Family history of depression
• Other illnesses
• Use of drugs or alcohol
• Extreme stress or grief
• Depression caused by a specific situation, sometimes triggers true depression

Symptoms of Depression

The period of time when you experience symptoms of depression is called an episode. An episode lasts at least two weeks with several symptoms occurring every day.

• Lack of interest in things that you normally enjoy
• Feeling sad, blue, or “down in the dumps”
• Feeling sluggish or restless, and not able to sleep
• Feeling worthless or guilty
• Experience a change in appetite with either weight gain or weight loss
• Thoughts of death or suicide, or attempt to commit suicide
• Problems concentrating, thinking, remembering or making decisions
• Sleeping too much or not able to fall asleep, or stay asleep through the night
• Lack of energy and feeling tired all of the time

Depression may vary in severity from mild to severe. If you have mild depression, you will only have a few symptoms. It takes an extra effort to do the things you have to do, but you can usually accomplish those tasks. Moderate depression means you have many symptoms, and you may not be able to do things you need to do. If you have severe depression, you have nearly all the symptoms of depression. This type of depression almost always keeps you from performing your daily tasks.

Diagnosing Depression

A doctor diagnoses depression after assessing both your physical and mental condition. In looking for the cause of your depression, the provider will ask questions about other medical problems, use of certain medications, and the use of drugs or alcohol. Blood chemistries, including a thyroid work-up should be current, and if not, will be ordered. If your doctor determines that a medical problem may be causing your depression, treating that problem may correct your depression.

Treatment of Depression

Treatment may include antidepressant medication, psychotherapy or both. Antidepressant medications are helpful and are used to treat mild, moderate and severe depression. Antidepressants relieve symptoms in more than half of the people who take them. They work by changing the balance of chemicals in the brain. Most people who take them start to feel better after a few weeks. There are several types of antidepressant medication. All antidepressant medications can have some side effects. About half the people who take them will experience some side effects early in their treatments, usually within the first 2 weeks. Side effects usually subside after 2 to 4 weeks.

Common Side Effects

Dry mouth

Nausea

Dizziness

Constipation

Skin rash

Feeling sleepy or having trouble sleeping

Gaining or losing weight

Feeling restless

Decreased sex drive (libido)

Serious Side Effects (uncommon):

Trouble urinating

Heart problem

Seizures

Fainting

Finding the Right Antidepressant Medications

When an anti-depressant medication is recommended to relieve the symptoms of depression, your doctor will prescribe one from the following categories:

A. SSRI’s (Selective Serotonin Reuptake Inhibitors)

First introduced in the 1980’s, the overall side effects of SSRI drugs tend to be less severe than the older antidepressants known as tricyclic (TCA) antidepressants and monoamine oxidase inhibitors (MAOI’s). SSRI’s helped restore the brain’s chemical balance by increasing the available supply of the chemical messenger called serotonin (a neurotransmitter). SSRI’s appear to relieve depression by increasing serotonin levels without affecting the other chemicals in the brain and have fewer side effects than those of the MAOI’s and TCA’s. Available SSRI’s include: Celexa, Lexapro, Paxil and Paxil CR, Prozac and Zoloft.

B. SNRI’s (Serotonin-Norepinephrine Reuptake Inhibitors)

Similar to the SSRI class of anti-depressants as discussed above, SNRI’s also blocks the reuptake of another neurotransmitter, norepinephrine, in addition to serotonin.

Available SNRI’s include:

• Remeron – good choice with weight loss, poor appetite or hypertension
• Serzone – similar to Remeron; good choice with insomnia or anxiety
• Effexor & Effexor XR – beneficial in anxiety and panic disorders
• Pristiq – works within 2 weeks; no weight gain; minimal sexual dysfunction.

C. Other Available Antidepressants

• Wellbutrin (Buproprion) – Blocks reuptake of dopamine. Cannot mix with alcohol, increases seizures; can cause weight loss.

For more information about depression contact the following organizations:

National Institute of Mental Health

6001 Executive Blvd., Room 8184 MSC 9663

Bethesda, MD 20892-9663

1-800-421-4211

http://www.nimh.nih.gov/publicat/depression.cfm

National Mental Health Association

1021 Prince Street

Alexandria, VA 22314-2971

1-800-969-NMHA (6602)

http://www.nmha.org

National Alliance of the Mentally Ill

Colonial Place 3

2107 Wilson Blvd., Suite 3000

Arlington, VA 22201-3042

1-800-950-NAMI (6264)

http://www.nami.org

If you would like more information about depression, contact Dr. Gordon C. Gunn MD at 714-912-2211 or visit www.gordongunnmd.com to schedule an appointment today. 

Dr. Gunn proudly serves Fullerton and all surrounding areas.